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The article discusses various research studies on cellular behavior and tissue engineering. The main topics include:* Matrix elasticity directing osteoblasts and osteocytes during bone formation under mechanical stress in vivo* Haematopoietic stem cells not transdifferentiating into cardiac myocytes in myocardial infarcts* Extracellular matrix organization modulating fibroblast growth and growth factor responsiveness* Actin cytoskeleton disruption inducing rapid morphological changes and mimicking neuronal phenotype in bone marrow stromal cells* Substrate flexibility regulating cell locomotion and focal adhesions* Multilineage potential of adult human mesenchymal stem cellsThese studies explore the interactions between cells, their microenvironment, and the mechanical properties of tissues, which are crucial for understanding various biological processes.